Publications


Publications

Wandrag L, Siervo M, Riley HL, Khosravi M, Fernandez BO, Carl A. Leckstrom CA, Martin DS, Mitchell K, Levett DZ, Montgomery HE, Mythen MG, Stroud MA, Grocott MP, Feelisch M, for the Caudwell Xtreme Everest Research Group
Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition


Siervo M, Riley HL, Fernandez BO, Leckstrom CA, Martin DS, Mitchell K, Levett DZ, Montgomery HE, Mythen MG, Grocott MP, Feelisch M; Caudwell Xtreme Everest Research Group.
Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation.
PLoS One 2014;9(4):e94915

Wilson MH, Davagnanam I, Holland G, Dattani RS, Tamm A, Hirani SP, Kolfschoten N, Strycharczuk L, Green C, Thornton JS, Wright A, Edsell M, Kitchen ND, Sharp DJ, Ham TE, Murray A, Holloway CJ, Clarke K, Grocott MP, Montgomery H, Imray C; Birmingham Medical Research Expeditionary Society and Caudwell Xtreme Everest Research Group.
Cerebral venous system and anatomical predisposition to high-altitude headache.
Annals of Neurology 2013;73(3):381-9


Martin DS, Pate J, Vercueil A, Doyle P, Mythen MG, Grocott MP for the Caudwell Extreme Everest Research Group.
Reduced coagulation at high altitude identified by thromboelastography
Thrombosis and Haemostasis 2012;107(6):1066-71


McMorrow RCN, Windsor JS, Hart ND, Richards P, Rodway GW, Ahuja VY, Dwyer MJ, Mythen MG, Grocott MPW, for the Caudwell Xtreme Everest Research Group.
Closed and open breathing circuit function in healthy volunteers during exercise at Mount Everest base camp (5300 m).
Anaesthesia 2012;67(8):875-80


Levett DZ, Radford EJ, Menassa DA, Graber FE, Hoppeler H, Martin DS, Ferguson-Smith AC, Montgomery HE, Grocott MPW, Murray AJ, for the Caudwell Extreme Everest Research Group.
Acclimatization of skeletal muscle mitochondria to high altitude hypoxia during an ascent of Everest
FASEB Journal 2012;26(4):1431-41


Levett DZ, Fernandez BO, Riley HL, Martin DS, Mitchell K, Leckstrom CA, Ince C, Whipp BJ, Mythen MG, Montgomery HE, Grocott MP, Feelisch M, for the Caudwell Extreme Everest Research Group.
The role of nitrogen oxides in human adaptation to hypoxia.
Scientific Reports 2011;1:109


Wilson MH, Mark Edsell M, Davagnanam I, Hirani SP, Martin D, Levett DZH, Thornton J, Golay X, Strycharczuk L, Newman S; Montgomery H; Grocott MPW and Imray CHE for the Caudwell Xtreme Everest Research Group.
Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia - an ultrasound and MRI study.
Journal of Cerebral Blood Flow and Metabolism 2011;31(10):2019-2029


Rodway GW, Edsell ME, Wong B, Windsor JS; Caudwell Xtreme Everest Research Group.
Sleep at Altitude: A Comparison of Therapies.
Wilderness and Environmental Medicine 2011;22(4):316-20


McMorrow RCN, Windsor JS, Mythen MG, Grocott MPW, Caudwell Xtreme Everest Research Group.
A novel ambulatory closed circuit breathing system for use during exercise.
Anaesthesia 2011 Mar 28. doi: 10.1111/j.1365-2044.2011.06698.x. [


Holloway CJ, Montgomery HE, Murray AJ, Cochlin LE, Codreanu I, Hopwood N, Johnson AW, Rider OJ, Levett DZ, Tyler DJ, Francis JM, Neubauer S, Grocott MP, Clarke K; for the Caudwell Xtreme Everest Research Group.
Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp.
FASEB Journal 2011;25(2):792-796


Levett DZH, Martin DS, Wilson MH, Mitchell K, Dhillon S, Rigat F, Montgomery HE, Mythen MG, Grocott MPW; for the Caudwell Xtreme Everest Research Group.
Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia.
BMC Medical Research Methodology 2010 Oct 21;10(1):98. (Epub ahead of print)


Edwards LM, Murray AJ, Tyler DJ, Kemp GJ, Holloway CJ, Robbins PA, Neubauer S, Levett D, Montgomery HE, Grocott MP, Clarke K for the Caudwell Xtreme Everest Research Group.
The Effect of High-Altitude on Human Skeletal Muscle Energetics: 31P-MRS Results from the Caudwell Xtreme Everest Expedition.
PLoS ONE 2010;5(5):e10681


Martin DS, Goedhart P, Vercueil A, Ince C, Levett DZH, Grocott MPW for the Caudwell Xtreme Everest Research Group.
Changes in sublingual microcirculatory flow index and vessel density on ascent to altitude.
Experimental Physiology 2010;95:880-891


Martin D, Levett DZH, Mythen M, Grocott MPW for the Caudwell Xtreme Everest Research Group.
Changes in skeletal muscle oxygenation during exercise measured by near infra-red spectroscopy on ascent to altitude.
Critical Care 2009;13(Suppl 5):S7


Grocott M, Martin D, Levett D, McMorrow R, Windsor J, Montgomery H for the Caudwell Xtreme Everest Research Group..
Arterial blood gases and oxygen content in climbers on Mount Everest.
New England Journal of Medicine 2009;360:140-149